Seasonal infections

Is it the period for seasonal infections?

With the Monsoon rains comes many infectious diseases that can pose health risks, such as mosquito-borne malaria and dengue.

Early suggestion for a likely diagnosis can save lives. However, many infections share the same symptoms and clinical findings. The combination of a detailed patient anamnesis, physical examination, and laboratory data is therefore a prerequisite for identification of the likely cause.

Diagnosing fever-related illnesses

Fig 1. Dengue Fever Symptoms

Considerations for a correct platelet count

  • PLT count is extremely important to decide the course of treatment of conditions such as dengue fever but it is time-consuming to manually check PLT count, especially during the rainy season when many cases occur and the workload in the clinics is high.
  • The high dilution level used by many automated hematology analyzers can make an accurate PLT count challenging when the number of PLTs per blood volume decreases.

Floating discriminator and extended PLT count

Boule hematology analyzers use a floating discriminator algorithm to distinguish between PLTs and RBCs, instead of a fixed discriminator, to ensure a reliable PLT count between PLT and RBC to count PLT as close as accurate by preventing microcytic RBCs to falsely be counted as PLTs.

picture describing Floating discriminator technique

Fig.2 Floating discriminator technique prevents microcytic RBCs to be falsely counted as PLTs and elevated PLTs to interfere with the RBC count


Fig 3. Extended PLT count is automatically triggered (if enabled) when PLT count is less than 50 × 109/L and RBC count is more than 0.5 × 1012/L


Boule analyzers incorporate two crucial features, Extended PLT count and Floating discriminator, to provide physicians with the most precise and dependable PLT count sample for accurate diagnosis and treatment of fever-related illnesses such as dengue fever.

Moreover, these analyzers come equipped with a micro-pipette adapter (MPA) inlet to facilitate the analysis of capillary samples (20 μL). In just one minute, the analyzers can generate reports for 22 parameters from a fingerstick sample. Collecting capillary blood is often simpler than venous blood, and fingerstick sampling can be more comfortable for the patient.

Medonic M32 and Swelab Alfa Plus hematology analyzer equiped with micro-pipette adapter (MPA) inlet.

Medonic M32 and Swelab Alfa Plus hematology analyzer equiped with micro-pipette adapter (MPA) inlet.


Learn more about Complete blood count and its utility in fever investigations

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