Clinical performance of Medonic M51 hematology analyzer compared with reference instrument
Figure 1. Medonic M51 is an entry-level 5-part hematology analyzer intended for the cost-minded clinical laboratory. The user-friendly design makes system operations easy. Robust software and hardware components ensure a reliable system performance. With its small footprint, Medonic M51 is well suited for the typical physician office laboratory.
Figure 2. Medonic M51 uses laser-based flow cytometry for WBC, with separate channels for 4-part and BASO differential. Low angle signal (about 1° to 5°) represents the cell volume information, middle angle signal (about 7° to 20°) represents the cell nucleus information, high angle signal (about 90°) represents the cell nucleus and cytoplasm information.
Figure 3. Agreement between the test and the reference systems. Passing-Bablok regression graphs for WBC (A), NEU% (B), LYM% (C), MONO% (D), EOS% (E), BASO% (F), RBC (G), and HGB (H). In regression plots, the gray line corresponds to identity (x = y) and the red line corresponds to best fit.
Figure 4. Agreement of the MONO count between (A) the test and the reference system, (B) the test system and manual microscopy, and (C) the reference system and manual microscopy using samples with WBC < 50 × 109/L (n = 138). In the regression plots, the gray line corresponds to identity (x = y) and the red line corresponds to best fit.