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Performance of Medonic M51 hematology system

Performance of Medonic M51 hematology system

Comparison of the performance of automated hematology analyzer Medonic M51 hematology system with a reference system intended for use in large hospital laboratory settings

Hematology analyses are routinely performed both by large clinical hospital laboratories on fully automated, high-throughput analyzers as well as by smaller physician’s office laboratories on stand-alone analyzers. As clinical laboratory tests form the basis for patient diagnosis, analyzer accuracy and precision are equality important independent of sample scale or clinical setting.

Medonic M51 – explore your possibilities

Medonic M51 is a automated hematology analyzer intended for the smaller laboratory (Fig 1). The analyzer provides information on 29 parameters for the CBC, including red blood cells (RBC) and platelets (PLT), hemoglobin (HGB), as well as a 5-part differential count of the WBCs.

Medonic M51 employs well-proven measurement technologies. The analyzer uses impedance for RBC and PLT counts, while the WBC differential is conducted by laser-based flow cytometry. HGB is determined spectrophotometrically.


Fig 1. Medonic M51 is a 5-part hematology analyzer intended for the cost-minded clinical laboratory. The user-friendly design makes system operations easy. Robust software and hardware components ensure a reliable system performance. With its small footprint, Medonic M51 is well suited for the typical physician office laboratory.

“More than 200 live samples with various value ranges were evaluated simultaneously in the test instrument Medonic M51 and reference instrument Beckman Coulter DxH 800 in the month of August 2018”, Dr Patwadkar explains. “The results show that Medonic M51 is in good agreement with the reference system. The analyzers provide similar conditions for patient decisions. Medonic M51 generated analytical data close to microscopic examination and is a good option for smaller clinical and hospital laboratories.”

Fig 2. Agreement between cell count in the Medonic M51 test and DxH 800 reference (Beckman Coulter) hematology analyzers. Passing-Bablok regression graphs are shown for (A) WBC, (B) RBC, (C) HGB, (D) MCV, (E) HCT, (F) RDW%, (G) PLT, and (H) MPV. In regression plots, the gray line is the line of identity (x = y) and the red line is the line of best fit.
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